Genetic testing for your cardiology patients
Why genetic testing is recommended in cardiomyopathy
State societies guidelines recommend genetic testing for many patients with cardiomyopathy. Despite this, only ~1% of patients are tested, and diagnostic delay is common.12
Identifying a pathogenic or likely pathogenic variant may:
Clarify etiology
Inform clinical management
Support risk stratification
Enable cascade testing for family members
Heartgene was created to improve access to genetic testing without increasing workflow complexity.
Clinical impact since launch
33%
diagnostic yield
pathogenic or likely pathogenic variants identified
20+
cardiovascular genes
with variants identified
50% of patients
with positive findings met 2025 AUC criteria for primary prevention ICD consideration
70% of positive patients
would not have qualified based on LVEF alone
The Heartgene testing model
Laboratory partnerships
Sequencing is performed by Broad Clinical Labs.
Variant interpretation is conducted in collaboration with Mass General Brigham’s Laboratory for Molecular Medicine (LMM), applying cardiovascular genetics expertise to reporting.
Genetic counseling is provided by licensed counselors through DNAVisit.
Sponsored access model
Testing is provided at no cost to eligible patients.
No prior authorization. No insurance billing.
No cost to practices.
Data use and privacy
Your patient’s identifiable health information is used only for clinical testing, interpretation, and result reporting. Heartgene does not sell your personal information.
To help advance understanding of genetic heart disease and improve care, de-identified data (without name or identifying details) may be shared with trusted clinical partners, research collaborators, or program sponsors if the patient chooses to opt in.
All data use follows applicable privacy laws and institutional standards. For full details see Heartgene Privacy Policy
Ready to implement
guideline-recommended testing?
Ask a Heartgene representative to contact you
Questions & Answers
Which patients qualify for testing?
Patients with a diagnosis of cardiomyopathy or channelopathy, or first-degree relatives of a patient who received a positive result through Heartgene.
How do I order a kit?
Clinicians can order kits from Heartgene and request kits to be sent to their clinic or directly to patients' homes. See the Provider Ordering Instructions for details.
Who provides sequencing and interprets the results?
Sequencing is performed at Broad Clinical Labs, and variant interpretation is conducted by Mass General Brigham's Laboratory for Molecular Medicine.
What is the turnaround time?
Most results are available within 6-8 to weeks of sample receipt.